For Clinicians

Artfun+ biomarker has multiple clinical applications on several unmet markets in primary and secondary prevention

The Core Of Our Biomarker Is The Measurement Of Ascending Aortic Distensibility By MRI

ArtFun+ is an MRI analysis software enabling leading cardiovascular clinicians to optimize their cardiac MRIs with a new imaging biomarker for cardiovascular risk stratification: the Ascending Aortic Distensibility (AAD). AAD measures the stiffness of the central arteries by precisely tracking how the aorta moves and combining this information with the pressure in theblood vessels.

AAD with ArtFun+ have been shown to be the The strongest predictor of CV events and death at 8.5 years for intermediate/low risk patients using traditional risk factors. AAD has also been shown to be a powerful marker of early subclinical cardiovascular (CV) disease and one of the earliest indicators of aging.

ArtFun+ allows qualified clinicians to complement their cardiac MRI exams with the analysis of axial cine SSFP of the aorta, enabling a deep understanding of patients’ cardiovascular health status.


new imaging biomarker for cardiovascular Age & risk Stratification

Biomarker of cardiovascular Risk: Early infraclinical disease, primary & secondary prevention.

Earliest marker of cardiovascular aging: Integrator of individual CV age and health over the lifespan.

Prime Determinant Of CV Efficiency: CV coupling and aortic function is a prime determinant of CV efficiency, making ArtFun+ measurements highly relevant to CV phenotyping.

Measured By MRI: Unique non-invasive assessment of the central arterial system

Reversible Biomarker: Quantifies rejuvenation

ArtFun+’ technology has shown that you could improve 4+ years of cardiovascular age by following a 6-months moderate sports program and other non-therapeutic prevention programs, as used at the London Bart’s Heart Center and highlighted on BBC News.


Designed For Cardiovascular Prevention

Discover CardioInspect, a clinical decision support tool powered by ArtFun+ biomarkers, providing personalized reports on cardiovascular age & risk in an intuitive and engaging format for clinicians and patients.

First positioning in primary prevention

ArtFun+’s Biomarkers for Cardiovascular Check-Ups

Prevents fatal cardiovascular events by identifying long-term cardiovascular risk.
It helps clinicians to start and monitor cardiovascular check ups, as well as to personalize management of patients by adjusting treatment and follow-up plan.


Beyond primary prevention

ArtFun+’s Biomarkers For Secondary Prevention

ArtFun+ is currently addressing aortic aneurysm & coronary artery diseases

Aortic Aneurysm

Predict the risk of aorta rupturing and help decide when to pre-emptively operate

coronary artery diseases

Predict recurrence ischemic events in premature coronary artery diseases

Beyond these programs

we aim to build a diversified portfolio of assets in different clinical applications

Systemic Impact Of High Central Vascular Stiffness

Heart

Myocardial Dysfunction & Heart Failure & Left Arterial Dysfunction & Reduced Coronary Flow Reserve

Brain

Subclinical Brain
& Pathology Cognitive
& Impairment / Dementia

Liver

Insulin Resistance
&
NASH

Kidney

Chronic Kidney Disease

Testicles

Testosterone Deficiency

Placenta-Fetal Unit

Pre-Eclampsia Intrauterine Growth Restriction

Let’s Drive Adoption

With More Clinical Applications